Tuesday, 21 October 2014

PERFECT Launch (3): Depression and its Benefits

Magdalena Antrobus
My research focuses on epistemic and pragmatic benefits of imperfect cognitions found in the clinical population. More specifically I am interested in acquiring answers related to the question of the possible positive sides of mental disorders.

It is commonly known that mental illness constitutes a source of profound harm. It relates to individual suffering, distorts one’s cognitive, emotional and behavioural processes, and sometimes leads to severe impairment. However, the results of more recent psychological studies indicate that psychiatric disorders might be linked to particular benefits as well as causing pain.

There has been a well-researched relationship between bipolar disorder and creativity. It is believed that certain clinical symptoms brought by the illness, for example thought speed or openness for new experiences, may contribute to enhanced creativity (see for instance Ghaemi, 2011; Andreasen, 2005; Jamison, 1996). (For more details see my interview with Greg Currie.) If that were true, we would have the grounds to believe that bipolar disorder brings certain epistemic benefits. At the same time the illness may cause cognitive impairments in other areas of functioning, for example it may affect memory, sleep and concentration. The idea that pragmatic or psychological harm may coexist with the benefits of an epistemic kind is relatively new in psychiatry, thus researching it seems very exciting.

Thursday, 16 October 2014

Interview with Martin Davies: Delusions (Part 3)


Martin Davies
This is the third part of an interview with Professor Martin Davies on delusions. (Although this part can be read independently of the previous two, you may want to read also the first and second part of the interview if you haven't done so already!)


LB: In the first stage of our project PERFECT we are going to ask whether delusions can have pragmatic and epistemic benefits. You and your collaborators have noticed how anosognosia (denial of illness), despite initially interfering with rehabilitation, can then lead to lower anxiety and protect from negative emotions (Aimola Davies et al., 2009). Can you think of other examples of delusions having a positive psychological impact? 

MKD: Let me begin by reviewing the findings that you mentioned in your question. Some researchers distinguish denial of illness from anosognosia and use the ‘denial’ terminology for cases with a ‘psychological’ rather than neurological aetiology. In our paper, we referred to a theoretical review by Kortte and Wegener (2004), who found support for both adaptive and maladaptive effects of denial of illness across a range of rehabilitation populations.

They proposed two distinctions to explain these different effects: (i) subtypes of denial and (ii) different time points from symptom identification to hospitalisation and rehabilitation. On (i), they suggested that the effect of avoidance of illness-related information is more likely to be maladaptive while a positive reinterpretation of the illness experience was more likely to be adaptive. On (ii), and focusing now on Kortte and Wegener’s discussion of denial of heart disease, denial at the stage of symptom (self-)identification has obvious negative consequences and long-term denial (particularly, of the avoidance type) after discharge from hospital has been linked with poorer compliance with medication regimes and a failure to heed medical advice about risk factors. However, denial (particularly, of the positive reinterpretation type) during the hospitalisation stage appears to be associated with more positive effects, such as protection from negative emotional states and reduced medical complications.

Tuesday, 14 October 2014

PERFECT Launch (2): Biological Function and Formation of Delusions

Our project logo.
My research so far has been on belief, and this is an area I will continue to focus on. I am interested in researching two main areas: first, how best to think about delusional beliefs when we look to the biological function of belief, and second, accounts of delusion formation.

In my PhD I defended a biological account of belief according to which our mechanisms of belief-production have (at least) two biological functions proper to them. The first is the function to produce true beliefs, and the second is the function to produce useful beliefs. When I say ‘useful’, I do not mean useful an approximation to truth, but rather useful with respect to facilitating the effective functioning of the believer. I was mainly concerned with explaining the connection between belief and truth, and so much of the work was done by appeal to the function of producing true beliefs. However, towards the end of my thesis, I gestured towards the kind of explanatory work which might be done by appeal to the function of producing useful belief.

In terms of future research I am very keen to think about how much work the functional account of belief I developed in my doctoral work can do when we look to pathological belief in the clinical population, specifically, delusional belief. I think there are several questions to ask about delusional belief in the context of my account. Firstly, what is the biological proper function of delusional belief?

Friday, 10 October 2014

Schizophrenia and Logic


Mental Health Awareness Weeks logo
Today, 10th October 2014, is World Mental Health Day. This year it is dedicated to living with schizophrenia. On this important occasion, Gareth Owen kindly agreed to discuss his fascinating work on schizophrenia and logic. Gareth is Clinical Senior Lecturer at the Institute of Psychiatry, Psychology and Neuroscience, King's College London.

People with schizophrenia do worse than others on many tasks. Indeed a global conclusion in the psychology of schizophrenia is that people with this disorder have somewhat lower IQ than those without – a conclusion that makes schizophrenia seem a disorder of cognition like dementia or learning disability. But this is an incomplete perspective. The phenomenology of schizophrenia also points in the direction of representational overactivity (1). Additionally, delusions, which people with schizophrenia often exhibit, are not explained by failures of formal inference such as inability to reason with modus ponens or modus tollens or inability to adhere to Bayesian updating norms. That is striking when one considers that delusion and illogically are often assumed to be the same.

Thursday, 9 October 2014

Interview with Martin Davies: Delusions (Part 2)

Martin Davies
This is the second part of an interview with Professor Martin Davies on delusions. You can read the first part of the interview here.


LB: Presentations of the two-factor account of delusion formation usually begin with two questions. The first question is about where the content of the delusion came from and the second is about the adoption or persistence of the belief. The two factors are supposed to provide answers to these two questions. But it sounds as if you are distinguishing a question about adoption from a question about persistence (or maintenance). If there are more than two questions to be answered, will an explanation of a delusion have to appeal to more than two factors?

MKD: Thank you for raising this issue of the relationship between questions and factors. It is quite important for understanding the two-factor framework. Questions about the aetiology of a delusion can be multiplied and, correspondingly, explanations of a delusion can be increasingly detailed, appealing to more than two ‘factors’ in the ordinary sense of that term. But, crucially, factors in the sense relevant to the two-factor framework are not just elements in an explanation. They are, specifically, pathologies or departures from normality, such as neuropsychological deficits.

You are right to say that I want to distinguish between a question about adoption of the delusional belief and a question about the belief’s persistence. If we are going to say something substantive about the nature of the second factor then we need to be clear about the role of the second factor. Where, in the total story of the aetiology of a delusion, does it figure? So, along with the first question about the source of the delusional idea or hypothesis, there should be the adoption question, ‘Why is the delusional hypothesis adopted as a belief?’, and the persistence question, ‘Why does that belief, once adopted, persist; why is it not subsequently rejected?’.

Tuesday, 7 October 2014

PERFECT Launch (1): False but Epistemically Beneficial Beliefs

In this post I would like to introduce our new project, PERFECT, which started a week ago and will last for five years. The next few weeks on the blog are dedicated to an initial exploration of
the project themes, with posts by team members and interviews with people who have inspired us.

(I interviewed Martin Davies, who was my PhD supervisor and introduced me to the psychological literature on delusions. The first part of the interview appeared here, and the second part will be published on Thursday).

The project is funded by a European Research Council Consolidator grant awarded to me last December. The funding allows me to explore a novel idea and provides the resources for building a team. Currently, the PERFECT team includes Ema Sullivan-Bissett (post-doc) and Magdalena Antrobus (PhD student) who are based in the Philosophy Department at the University of Birmingham. Other two post-doctoral researchers and another PhD student will join the team at a later stage. The Co-Investigator is Michael Larkin from the School of Psychology at the University of Birmingham.

The novel idea we wish to explore is that even cognitions that are factually inaccurate can have benefits for the acquisition of knowledge. This is counterintuitive as most would agree that inaccurate cognitions can at best benefit an agent pragmatically, by enhancing their wellbeing (short- or long-term) or by conferring them other practical advantages, but undermine knowledge of the self or of the surrounding physical and social world. In the first part of the project, we want to focus on BELIEFS that are false and irrational, and that may be common in the non-clinical population or appear as symptoms of psychiatric disorders. Next, we will look at memories, narratives and explanations.